Niemierko A, Goitein M
Department of Radiation Oncology, Massachusetts General Hospital, Boston 02114.
Med Phys. 1994 Jan;21(1):3-11. doi: 10.1118/1.597361.
A new approach to calculating and displaying dose-volume relationships in 3D radiation therapy is presented. We have developed a concept of a dose-volume distribution (DVD) and its corresponding differential dose-volume distribution (DDVD), based on organization of the data in the volume rather than in the dose domain. The new concepts make full use of the information that can be obtained from the dose calculation points and the sampling pattern and are designed to overcome shortcomings of the classical concepts of dose-volume histograms (DVH) and differential dose-volume histograms (DDVH). The new concepts can be applied to any number of dose calculation points, but they are especially advantageous when a small number of points is used. DVDs are particularly well suited to pseudo- and quasi-random sampling of dose distributions. We have developed an error analysis for DVDs and DDVDs in the case of pseudorandom sampling. We also describe an adaptive technique for minimizing the amount of data needed for purposes of display.
本文提出了一种在三维放射治疗中计算和显示剂量-体积关系的新方法。我们基于体积中的数据组织而非剂量域，开发了剂量-体积分布（DVD）及其相应的微分剂量-体积分布（DDVD）的概念。这些新概念充分利用了可从剂量计算点和采样模式获得的信息，旨在克服剂量-体积直方图（DVH）和微分剂量-体积直方图（DDVH）经典概念的缺点。新概念可应用于任意数量的剂量计算点，但在使用少量点时尤其有利。DVD特别适合剂量分布的伪随机和准随机采样。我们针对伪随机采样情况开发了DVD和DDVD的误差分析。我们还描述了一种自适应技术，用于最小化显示所需的数据量。
