Dieterle L, Becker E W, Berg P A, Berkenfeld R, Reinshagen G
Erwachsenenklinik am Epilepsiezentrum Kork, Medizinischen Universitätsklinik Tübingen.
Nervenarzt. 1994 Feb;65(2):122-4.
A patient with focal epilepsy that was resistant to medical treatment received add-on therapy with vigabatrin. Six months after commencement of vigabatrin therapy, allergic vasculitis caused by vigabatrin was diagnosed. The patient displayed unilateral anterior ischaemic optic neuropathy with impairment of vision and concentric loss of visual field. The diagnosis was based on the lymphocyte transformation test and the clinical course. The allergic vasculitis was healed by cortisone therapy.
一名对药物治疗耐药的局灶性癫痫患者接受了加用氨己烯酸的治疗。氨己烯酸治疗开始6个月后,诊断出由氨己烯酸引起的过敏性血管炎。该患者表现为单侧前部缺血性视神经病变,伴有视力损害和视野同心性缺损。诊断基于淋巴细胞转化试验和临床病程。过敏性血管炎通过皮质类固醇治疗得以治愈。