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苏丹由不同种类利什曼原虫引起的鼻利什曼病。不同临床形式的鉴别特征。

Leishmaniasis of the nose caused by different species of Leishmania in the Sudan. Distinguishing features of the different clinical forms.

作者信息

el-Hassan A M, Yagi H I, Zijlstra E E, el-Kadarow A I

机构信息

Department of Surgery, Faculty of Medicine, University of Khartoum, Sudan.

出版信息

Trop Geogr Med. 1994;46(1):33-6.

PMID:8165735
Abstract

The nasal mucosa is affected in mucosal leishmaniasis and the skin of the nose, but not the mucosa, may be involved in cutaneous leishmaniasis (oriental sore) and in post kala-azar dermal leishmaniasis (PKDL). These clinical forms all occur in the Sudan and, particularly when advanced, may be confused with each other since mucosal leishmaniasis may extend to the skin of the upper lip and both cutaneous leishmaniasis and PKDL may spread to the anterior nares although they do not extend into the mucosa. Illustrative examples of the three conditions are described. Distinctive features of each form are given. The importance of making the correct diagnosis is stressed, since the different forms respond differently to anti-leishmanial drugs.

摘要

鼻黏膜在黏膜利什曼病中会受到影响,而在皮肤利什曼病(东方疖)和黑热病后皮肤利什曼病(PKDL)中,鼻子的皮肤会受累,但鼻黏膜不受累。这些临床类型在苏丹均有发生,尤其是病情严重时,它们可能会相互混淆,因为黏膜利什曼病可能会蔓延至上唇皮肤,而皮肤利什曼病和PKDL尽管不会蔓延至鼻黏膜,但可能会扩散至前鼻孔。文中描述了这三种病症的典型病例,并给出了每种类型的显著特征。强调了做出正确诊断的重要性,因为不同类型对抗利什曼药物的反应不同。

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