Cina S J, Conradi S E
Charleston County Medical Examiner's Office, Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston 29425.
Am J Forensic Med Pathol. 1994 Mar;15(1):28-31. doi: 10.1097/00000433-199403000-00007.
Acute pancreatitis has been the cause of death in several patients with AIDS and AIDS-related complex (ARC). Documented etiologies include several microorganisms and adverse drug reactions. We present a case of an HIV-positive prison inmate who died of acute necrotizing pancreatitis. Although he was infected with Mycobacterium avium-intracellulare, it is more likely that 2',3'-dideoxyinosine, an antiretroviral agent, induced pancreatitis. It is important to obtain a thorough pharmaceutical history in HIV-positive patients. Fatal medicinal reactions may result in death in ARC or AIDS patients. Documentation of opportunistic infection in AIDS patients may prove difficult and expensive, but costs may be minimized and diagnostic accuracy optimized if appropriate tissue samples, including lymph nodes, are submitted for histologic analysis.
急性胰腺炎已成为数例艾滋病患者及艾滋病相关综合征（ARC）患者的死因。已证实的病因包括多种微生物及药物不良反应。我们报告一例死于急性坏死性胰腺炎的HIV阳性监狱囚犯病例。尽管他感染了鸟分枝杆菌胞内菌，但更有可能是抗逆转录病毒药物2',3'-双脱氧肌苷诱发了胰腺炎。对HIV阳性患者详细了解用药史很重要。致命的药物反应可能导致ARC或艾滋病患者死亡。对艾滋病患者机会性感染的诊断可能困难且费用高昂，但如果提交包括淋巴结在内的适当组织样本进行组织学分析，可将费用降至最低并优化诊断准确性。
