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致命性胰腺炎作为HIV感染治疗的一种并发症。

Fatal pancreatitis as a complication of therapy for HIV infection.

作者信息

Pelucio M T, Rothenhaus T, Smith M, Ward D J

机构信息

Department of Emergency Medicine, Ronald Reagan Institute of Emergency Medicine, George Washington University Medical Center, Washington, District of Columbia, USA.

出版信息

J Emerg Med. 1995 Sep-Oct;13(5):633-7. doi: 10.1016/0736-4679(95)00068-l.

DOI:10.1016/0736-4679(95)00068-l
PMID:8530781
Abstract

Acute pancreatitis in HIV-infected patients with or without AIDS has been reported with increasing frequency over the past several years. Drugs used to treat HIV-infected patients are often the cause. We report a case of a 46-year-old HIV-infected man who presented to the emergency department with abdominal pain and was diagnosed with acute pancreatitis. The patient had recently begun taking 2',3'-dideoxyinosine (ddI). He died shortly after admission to the hospital; CT scan and autopsy confirmed the cause of death as hemorrhagic pancreatitis. We briefly review the literature on the incidence and severity of pancreatitis in association with ddI and pentamidine therapy.

摘要

在过去几年中,有或没有艾滋病的HIV感染患者发生急性胰腺炎的报道越来越多。用于治疗HIV感染患者的药物常常是病因。我们报告一例46岁的HIV感染男性患者,他因腹痛就诊于急诊科,被诊断为急性胰腺炎。该患者最近开始服用2',3'-双脱氧肌苷(ddI)。他入院后不久死亡;CT扫描和尸检证实死亡原因是出血性胰腺炎。我们简要回顾了与ddI和喷他脒治疗相关的胰腺炎发病率和严重程度的文献。

相似文献

1
Fatal pancreatitis as a complication of therapy for HIV infection.致命性胰腺炎作为HIV感染治疗的一种并发症。
J Emerg Med. 1995 Sep-Oct;13(5):633-7. doi: 10.1016/0736-4679(95)00068-l.
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Pancreatitis during intravenous pentamidine therapy in an AIDS patient with prior exposure to didanosine.一名曾接触过去羟肌苷的艾滋病患者在静脉注射喷他脒治疗期间发生胰腺炎。
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Incidence of pancreatitis in HIV-infected patients receiving nucleoside reverse transcriptase inhibitor drugs.接受核苷类逆转录酶抑制剂药物治疗的HIV感染患者中胰腺炎的发病率。
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Acute pancreatitis as a common complication of 2',3'-dideoxyinosine therapy in the acquired immunodeficiency syndrome.急性胰腺炎是获得性免疫缺陷综合征中2',3'-双脱氧肌苷治疗的常见并发症。
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The role of antiretroviral therapy in the incidence of pancreatitis in HIV-positive individuals in the EuroSIDA study.在欧洲艾滋病临床数据库(EuroSIDA)研究中抗逆转录病毒疗法在HIV阳性个体胰腺炎发病率中的作用。
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引用本文的文献

1
Nanotechnological approaches for pentamidine delivery.纳米技术在喷他脒传递中的应用。
Drug Deliv Transl Res. 2022 Aug;12(8):1911-1927. doi: 10.1007/s13346-022-01127-4. Epub 2022 Feb 25.
2
Antiretroviral drugs and acute pancreatitis in HIV/AIDS patients: is there any association? A literature review.抗逆转录病毒药物与HIV/AIDS患者的急性胰腺炎:存在关联吗?一项文献综述。
Einstein (Sao Paulo). 2014 Jan-Mar;12(1):112-9. doi: 10.1590/s1679-45082014rw2561.