Abballe C, Camaioni D, Mascaro A, Boccardi M, Evangelista M
Istituto di Anestesiologia e Rianimazione, Università Cattolica del Sacro Cuore, Roma.
G Chir. 1993 Dec;14(9):493-5.
A study carried out on 44 patients undergoing laparoscopic cholecystectomy was started in order to evaluate if nitrous oxide is or not contraindicated. The patients were divided in two groups of 22 subjects receiving or not nitrous oxide in the anaesthetic mixture. All the patients received the same preanaesthetic medication (diazepam and atrophine), thiopental and fentanyl as induction drugs, vecuronium as muscle relaxant and isoflurane for maintenance of anaesthesia. Bowel distension, technical difficulty, incidence of postoperative nausea and vomiting were examined. Our conclusions were that nitrous oxide has no clinically deleterious effects during laparoscopic cholecystectomy.
为了评估氧化亚氮是否为禁忌，对44例行腹腔镜胆囊切除术的患者进行了一项研究。患者被分为两组，每组22名受试者，麻醉混合剂中分别使用或不使用氧化亚氮。所有患者均接受相同的麻醉前用药（地西泮和阿托品）、硫喷妥钠和芬太尼作为诱导药物、维库溴铵作为肌肉松弛剂以及异氟烷用于维持麻醉。检查了肠扩张、技术难度、术后恶心和呕吐的发生率。我们的结论是，在腹腔镜胆囊切除术期间，氧化亚氮没有临床有害影响。
