Koyama S, Koh H, Noda K, Tagami N, Asada A
Department of Anesthesia, Hoshigaoka-kohseinenkin Hospital, Hirakata.
Masui. 1998 Mar;47(3):286-9.
We compared the incidence of postoperative nausea and vomiting after total intravenous propofol-fentanyl anesthesia (TIVA group) and that after thiamylal-nitrous oxide-isoflurane anesthesia (GOI group) in 60 ASA physical I and II patients for elective abdominal simple total hysterectomy. When the patients returned to the ward, the incidence of nausea was lower in TIVA group than in GOI group (P < 0.05), but no difference was found in the incidence of vomiting between the two groups. There were no differences in the incidence of nausea and vomiting 6 hours after the operation and on the next morning between the two groups. Postoperative pain scores were similar between the two groups, while total postoperative evaluation scores (nausea, vomiting, pain, fever, and sleep disturbance) were lower in TIVA group (P < 0.05). We conclude that TIVA with propofol-fentanyl reduced the incidence of nausea and improved total evaluation scores in the immediate postoperative period.
我们比较了60例美国麻醉医师协会（ASA）身体状况为I级和II级、择期行腹部单纯全子宫切除术患者在全凭静脉丙泊酚-芬太尼麻醉（TIVA组）和硫喷妥钠-氧化亚氮-异氟烷麻醉（GOI组）后术后恶心呕吐的发生率。当患者返回病房时，TIVA组恶心的发生率低于GOI组（P<0.05），但两组呕吐发生率无差异。两组术后6小时及次日早晨恶心呕吐发生率无差异。两组术后疼痛评分相似，而TIVA组术后总体评估评分（恶心、呕吐、疼痛、发热和睡眠障碍）较低（P<0.05）。我们得出结论，丙泊酚-芬太尼全凭静脉麻醉降低了术后即刻恶心的发生率，并改善了总体评估评分。
