Deepak K K, Manchanda S K, Maheshwari M C
Department of Physiology, All India Institute of Medical Sciences, New Delhi.
Biofeedback Self Regul. 1994 Mar;19(1):25-40. doi: 10.1007/BF01720668.
Eleven adults suffering from drug-resistant epilepsies were given meditation practice, while another nine adults acted as waiting list controls. All patients were on antiepileptic drugs and their serum drug levels were monitored regularly. Patients in the intervention group were given training in meditation, and they practiced meditation 20 minutes a day for one year. They showed a significant reduction in seizure frequency and duration, an increase in the dominant background EEG frequency, a reduction in mean spectral intensity of the 0.7-7.7 Hz segment, and an increment in mean spectral intensity in the 8-12 Hz segment of the EEG. All changes were statistically significant. Control patients did not show significant changes in seizure frequency and duration during the observation period of one year. The results indicate that continued meditation practice is of substantial help in improving the clinicoelectrographic picture in drug-resistant epileptics.
11名患有耐药性癫痫的成年人接受了冥想练习，另有9名成年人作为候补对照。所有患者均服用抗癫痫药物，并定期监测其血清药物水平。干预组的患者接受了冥想训练，他们每天练习冥想20分钟，持续一年。他们的癫痫发作频率和持续时间显著降低，优势背景脑电图频率增加，0.7-7.7赫兹频段的平均频谱强度降低，脑电图8-12赫兹频段的平均频谱强度增加。所有变化均具有统计学意义。在一年的观察期内，对照患者的癫痫发作频率和持续时间没有显著变化。结果表明，持续的冥想练习对改善耐药性癫痫患者的临床脑电图表现有很大帮助。
