Oken A C, Frank S M, Merritt W T, Fair J, Klein A, Burdick J, Thompson S, Beattie C
Department of Anesthesiology, Johns Hopkins Hospital, Baltimore, MD 21205.
J Cardiothorac Vasc Anesth. 1994 Feb;8(1):58-60. doi: 10.1016/1053-0770(94)90013-2.
Partial veno-venous bypass (VVB) is commonly used in orthotopic liver transplantation (OLT). Venous access for blood return during VVB classically uses a surgical cutdown on the left axillary vein (LAV), which may prolong operating time and can be associated with significant complications. The authors have developed an alternative means of establishing venous access whereby the anesthesia team places 8.5F venous cannulae preoperatively in one or two vessels (internal jugular, antecubital, or subclavian) percutaneously using the Seldinger technique. These cannulae then serve to accept venous return from below the diaphragm via a centrifugal pump. The aim fo the present study was to compare the hemodynamic profiles obtained during the anhepatic phase of OLT in patients in whom either a conventional LAV catheter (group 1) or percutaneous catheters (group 2) were used for return flow from a centrifugal pump. There were no identifiable complications related to venous access in either group of patients. Total operating room time was 800 +/- 30 minutes in group 1 and 720 +/- 40 minutes in group 2 (P = 0.17). Hemodynamic parameters were determined from continuous strip chart recordings of arterial, right atrial, and inferior vena caval (IVCP) pressures. Cardiac output (CO) was measured by thermodilution whereas pump flow was determined by an electromagnetic probe. Renal perfusion pressure (RPP) was calculated as the difference between mean arterial pressure (MAP) and IVCP. Bypass pump flow was greater, but not significantly different between group 1 (3.0 +/- 0.2 L/min) and group 2 (2.4 +/- 0.2 L/min) (P = 0.09).(ABSTRACT TRUNCATED AT 250 WORDS)
部分静脉 - 静脉转流(VVB)常用于原位肝移植(OLT)。在VVB期间,经典的血液回流通路是通过切开左腋静脉(LAV)进行手术插管,这可能会延长手术时间并伴有严重并发症。作者开发了一种替代的静脉通路建立方法,即麻醉团队术前使用Seldinger技术经皮在一根或两根血管(颈内静脉、肘前静脉或锁骨下静脉)中放置8.5F静脉插管。然后这些插管用于通过离心泵接受来自膈肌以下的静脉回流。本研究的目的是比较在OLT无肝期使用传统LAV导管(第1组)或经皮导管(第2组)进行离心泵回流的患者的血流动力学情况。两组患者均未出现与静脉通路相关的可识别并发症。第1组的总手术室时间为800±30分钟,第2组为720±40分钟(P = 0.17)。血流动力学参数通过动脉、右心房和下腔静脉(IVCP)压力的连续带状图表记录来确定。心输出量(CO)通过热稀释法测量,而泵流量通过电磁探头确定。肾灌注压(RPP)计算为平均动脉压(MAP)与IVCP之差。第1组(3.0±0.2 L/min)的旁路泵流量更大,但与第2组(2.4±0.2 L/min)无显著差异(P = 0.09)。(摘要截断于250字)