Hepatitis B markers in Gloucestershire firemen.

Occupational exposure to blood and body fluids and the prevalence of serological markers of hepatitis B virus (HBV) infection were studied in Gloucestershire firemen to assess the occupational risk of HBV infection. A high compliance was achieved (472/503, 94 per cent). Cumulative occupational exposure to blood or body fluids rose progressively to 68 per cent after 24 years' service. No sera were positive for hepatitis B surface antigen (HBsAg). Six sera were positive for hepatitis B surface antibody (anti-HBs) and were tested for hepatitis B core antibody (anti-HBc). The four subjects who were positive for anti-HBs alone had all received HBV vaccine. Two sera contained both anti-HBs and anti-HBc. Therefore, 2/472 firemen (0.42 per cent) showed evidence of previous HBV infection, a similar proportion to that found in a recent study in UK blood donors (0.49 per cent). Despite considerable exposure to blood and body fluids, an occupational risk of hepatitis B infection was not found in Gloucestershire firemen.