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西约克郡消防员的乙肝标志物

Hepatitis B markers in West Yorkshire firemen.

作者信息

Crosse B A, Teale C, Lees E M

机构信息

Department of Infectious Diseases, Seacroft Hospital, Leeds.

出版信息

Epidemiol Infect. 1989 Oct;103(2):383-5. doi: 10.1017/s0950268800030739.

Abstract

Firemen have been considered at occupational risk of hepatitis (HBV) infection, but proof is lacking. The aim of this study was to assess the degree of risk by determining the prevalence of serological markers of past infection with HBV in members of the West Yorkshire Fire Service. Sera from 173 firemen, 9.3% of the brigade, were tested for antibodies to HBV surface antigen and to core antigen. Those containing anti-HBs greater than or equal to 10 IU/L or anti-core antibody, were also tested for antibody to HBe antigen. The presence of more than one marker was used to define past infection. One sample satisfied this criterion, giving a prevalence rate of 0.6%. This compares with a rate of 1% in London blood donors. We conclude that the group shows no evidence of having been at increased risk of HBV infection. A comprehensive vaccination policy for firemen might be questionable.

摘要

消防员一直被认为有感染乙型肝炎(HBV)的职业风险,但缺乏证据。本研究的目的是通过确定西约克郡消防队成员过去感染HBV的血清学标志物的流行率来评估风险程度。对来自该消防队9.3%的173名消防员的血清进行了HBV表面抗原和核心抗原抗体检测。对那些抗-HBs大于或等于10 IU/L或抗核心抗体阳性的样本,也检测了HBe抗原抗体。存在一种以上标志物被用来定义过去的感染。有一个样本符合该标准,患病率为0.6%。这与伦敦献血者1%的患病率相比。我们得出结论,该群体没有证据表明有更高的HBV感染风险。针对消防员的全面疫苗接种政策可能存在疑问。

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