Ellis P, Cunningham D
Cancer Research Campaign Section of Medicine, Sutton, Surrey.
BMJ. 1994 Mar 26;308(6932):834-8. doi: 10.1136/bmj.308.6932.834.
Patients with oesophageal, gastric, and pancreatic carcinomas present a common and difficult problem for the clinician. Surgery is the best option for curative treatment but overall survival figures remain low. Recent improvements in our understanding of the biology of these tumours and improvements in their clinical staging, along with the development of combined modality approaches to local-regional disease, have led to renewed optimism that survival figures may be improved. This is particularly so for oesophageal and gastric carcinomas. In addition, there have been advances in the palliative management of all three tumours. This article examines some of these developments and looks at future prospects.
食管癌、胃癌和胰腺癌患者给临床医生带来了一个常见且棘手的问题。手术是根治性治疗的最佳选择，但总体生存率仍然很低。近年来，我们对这些肿瘤生物学特性的认识有所提高，其临床分期也得到改善，同时针对局部区域性疾病的综合治疗方法不断发展，这让人们重新燃起了提高生存率的乐观期望。食管癌和胃癌尤其如此。此外，这三种肿瘤的姑息治疗也取得了进展。本文探讨了其中的一些进展，并展望了未来前景。
