Chap L, Nimer S D
Department of Medicine, UCLA School of Medicine.
Leuk Lymphoma. 1994 Jan;12(3-4):315-6. doi: 10.3109/10428199409059604.
Low dose radiotherapy has been used to treat a variety of benign disorders including Histiocytosis X. Ionizing radiation may be leukemogenic with leukemia developing between 3.5 to 11 years after exposure. Twenty to 30% of these leukemias are chronic myelogenous leukemia (CML). In this report the rare development of PH1 + CML 11 years after radiation therapy for Histiocytosis X is recorded.
低剂量放疗已被用于治疗包括组织细胞增多症X在内的多种良性疾病。电离辐射可能具有致白血病作用，白血病会在接触辐射后3.5至11年发生。这些白血病中有20%至30%是慢性粒细胞白血病（CML）。在本报告中，记录了1例组织细胞增多症X放疗11年后罕见发生的PH1 + CML病例。
