NADPH氧化酶的结构：膜成分 - Suppr

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超能文献

Structure of the NADPH-oxidase: membrane components.

作者信息

Segal A W

机构信息

Department of Medicine, University College London.

出版信息

Immunodeficiency. 1993;4(1-4):167-79.

PMID:8167695

Abstract

摘要

相似文献

Structure of the NADPH-oxidase: membrane components.NADPH氧化酶的结构：膜成分

Immunodeficiency. 1993;4(1-4):167-79.

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Cytochrome b-245 is a flavocytochrome containing FAD and the NADPH-binding site of the microbicidal oxidase of phagocytes.细胞色素b - 245是一种含黄素细胞色素，含有FAD和吞噬细胞杀菌氧化酶的NADPH结合位点。

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Membrane association of Rac is required for high activity of the respiratory burst oxidase.呼吸爆发氧化酶的高活性需要Rac与膜结合。

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Leu505 of Nox2 is crucial for optimal p67phox-dependent activation of the flavocytochrome b558 during phagocytic NADPH oxidase assembly.在吞噬性NADPH氧化酶组装过程中，Nox2的亮氨酸505对于黄素细胞色素b558依赖p67phox的最佳激活至关重要。

J Leukoc Biol. 2007 Jan;81(1):238-49. doi: 10.1189/jlb.0905541. Epub 2006 Oct 23.

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A rise in ionized calcium activates the neutrophil NADPH-oxidase but is not sufficient to directly translocate cytosolic p47phox or p67phox to b cytochrome containing membranes.游离钙水平升高会激活中性粒细胞NADPH氧化酶，但不足以直接将胞质p47phox或p67phox转运至含b细胞色素的膜上。

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