Okamura K, Yuge I, Kawazoe K, Kitamura N, Imamura E, Koyanagi H, Konno S
J Cardiovasc Surg (Torino). 1976 Mar-Apr;17(2):178-86.
Morphological observations have been presented on 10 metaperiodate-glutaraldehyde-preserved aortic heterograft valves and 5 pulmonary heterograft valves implanted into the tricuspid position for periods ranging from 7 to 183 days. It is recognized that there was a relatively minimal histological change in pulmonary valves. However, calcification of implanted aortic cusps was observed in 20% (2 out of 10) of cases and high incidence of thrombus formation on aortic cusps was recognized, although there were none on pulmonary cusps. It seems reasonable to presume that the high incidence of thrombus formation on the aortic valves is primarily due to the decreased pliability and stiffness of the cusps. It is concluded that the pulmonary valves rather than the aortic valves are recommended for tricuspid valve replacement.
对10个经高碘酸盐 - 戊二醛保存的主动脉异种移植瓣膜和5个植入三尖瓣位置7至183天的肺动脉异种移植瓣膜进行了形态学观察。已认识到肺动脉瓣的组织学变化相对较小。然而，在10例中有2例（20%）观察到植入的主动脉瓣叶钙化，并且认识到主动脉瓣叶上血栓形成的发生率很高，而肺动脉瓣叶上没有血栓形成。推测主动脉瓣上血栓形成的高发生率主要是由于瓣叶柔韧性和顺应性降低似乎是合理的。结论是，三尖瓣置换推荐使用肺动脉瓣而非主动脉瓣。
