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关于戊二醛处理的异种心脏瓣膜的观察

Observations on glutaraldehyde-treated heterologous cardiac valves.

作者信息

Bodnar E, Olsen E G, Ross D N

出版信息

Thorax. 1979 Dec;34(6):794-800. doi: 10.1136/thx.34.6.794.

DOI:10.1136/thx.34.6.794
PMID:120617
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC471199/
Abstract

Recent publications on commercial porcine bioprosthetic cardiac valves have stated that the endothelium disappears during the glutaraldehyde processing and that in many cases histological evidence of early tissue deterioration was found. Our experiences have shown that porcine aortic valves can be processed in glutaraldehyde without loss of the integrity of the endothelium and with the development of optimum collagen fibre structure. The valve mounted in a Dacron tube is not restricted in diameter and performs well under biological conditions up to a period of six months.

摘要

近期有关商用猪生物心脏瓣膜的出版物称,在戊二醛处理过程中内皮细胞会消失,并且在许多情况下发现了早期组织退化的组织学证据。我们的经验表明,猪主动脉瓣可以在戊二醛中进行处理,而不会丧失内皮细胞的完整性,并且能形成最佳的胶原纤维结构。安装在涤纶管中的瓣膜直径不受限制,在长达六个月的生物条件下性能良好。

相似文献

1
Observations on glutaraldehyde-treated heterologous cardiac valves.关于戊二醛处理的异种心脏瓣膜的观察
Thorax. 1979 Dec;34(6):794-800. doi: 10.1136/thx.34.6.794.
2
A comparative study between glutaraldehyde-preserved aortic and pulmonary heterograft valves in the tricuspid position in dogs.犬三尖瓣位置戊二醛保存的主动脉和肺动脉异种移植瓣膜的比较研究。
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3
Antigen depressant effect of glutaraldehyde for aortic heterografts with a valve, with special reference to a concentration right fit for the preservation of grafts.戊二醛对带瓣主动脉异种移植物的抗原抑制作用,特别提及适合移植物保存的浓度
Surgery. 1980 Feb;87(2):170-6.
4
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Platelet adherence to bioprosthetic cardiac valves.血小板对生物人工心脏瓣膜的黏附。
Am J Cardiol. 1984 Mar 15;53(7):945-9. doi: 10.1016/0002-9149(84)90530-7.
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本文引用的文献

1
Studies on the character and staining of fibrin.纤维蛋白的特性及染色研究。
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Heart valve replacement with the Ionescu-Shiley pericardial xenograft.采用伊奥内斯库-希利心包异种移植物进行心脏瓣膜置换术。
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The porcine aortic valve bioprosthesis: a significant alternative.猪主动脉瓣生物假体:一种重要的替代物。
Ann Thorac Surg. 1976 Jun;21(6):573-5. doi: 10.1016/s0003-4975(10)63935-5.
5
Valve replacement with the Starr-Edwards and Hancock prostheses: comparative analysis of late morbidity and mortality.使用斯塔尔-爱德华兹和汉考克人工瓣膜进行瓣膜置换术:晚期发病率和死亡率的比较分析。
Ann Surg. 1977 Sep;186(3):301-9. doi: 10.1097/00000658-197709000-00008.
6
Pathologic findings after cardiac valve replacement with glutaraldehyde-fixed porcine valves.用戊二醛固定的猪瓣膜进行心脏瓣膜置换术后的病理结果。
Am J Cardiol. 1977 Sep;40(3):331-7. doi: 10.1016/0002-9149(77)90154-0.
7
Structural changes in porcine xenografts used as substitute cardiac valves. Gross and histologic observations in 51 glutaraldehyde-preserved Hancock valves in 41 patients.
Am J Cardiol. 1977 Sep;40(3):319-30. doi: 10.1016/0002-9149(77)90153-9.
8
Section of tissue or prosthetic valve. A five-year prospective, randomized comparison.组织或人工瓣膜切片。一项为期五年的前瞻性随机对照研究。
J Thorac Cardiovasc Surg. 1977 Jan;73(1):43-53.
9
Structural alterations of the porcine heterograft after various durations of implantation.不同植入时长后猪异种移植物的结构改变。
Am J Cardiol. 1978 Jun;41(7):1185-90. doi: 10.1016/0002-9149(78)90874-3.
10
Structural changes in glutaraldehyde-treated porcine heterografts used as substitute cardiac valves. Transmission and scanning electron microscopic observations in 12 patients.用作替代心脏瓣膜的戊二醛处理猪异种移植物的结构变化。12例患者的透射和扫描电子显微镜观察。
Am J Cardiol. 1978 Jun;41(7):1159-84. doi: 10.1016/0002-9149(78)90873-1.