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Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility.用沙眼衣原体小鼠肺炎生物变种对小鼠进行阴道内接种会导致不育。
Infect Immun. 1994 May;62(5):2094-7. doi: 10.1128/iai.62.5.2094-2097.1994.
2
Induction of protective immunity against a Chlamydia trachomatis genital infection in three genetically distinct strains of mice.在三种基因不同的小鼠品系中诱导针对沙眼衣原体生殖道感染的保护性免疫。
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3
Induction of infertility by the Chlamydia trachomatis mouse pneumonitis biovar in strains of mice that differ in their response to the 60 kDa heat shock protein.
J Reprod Fertil. 1994 Jul;101(2):287-94. doi: 10.1530/jrf.0.1010287.
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Factors influencing the induction of infertility in a mouse model of Chlamydia trachomatis ascending genital tract infection.沙眼衣原体上行性生殖道感染小鼠模型中影响不育诱导的因素。
J Med Microbiol. 1998 Jul;47(7):599-605. doi: 10.1099/00222615-47-7-599.
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Protection against infertility in a BALB/c mouse salpingitis model by intranasal immunization with the mouse pneumonitis biovar of Chlamydia trachomatis.通过用沙眼衣原体小鼠肺炎生物变种进行鼻内免疫在BALB/c小鼠输卵管炎模型中预防不孕
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Infect Immun. 1996 Dec;64(12):5341-8. doi: 10.1128/iai.64.12.5341-5348.1996.

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本文引用的文献

1
AN UNIDENTIFIED VIRUS WHICH PRODUCES PNEUMONIA AND SYSTEMIC INFECTION IN MICE.一种在小鼠中引发肺炎和全身感染的未鉴定病毒。
Science. 1942 Jan 9;95(2454):49-50. doi: 10.1126/science.95.2454.49-a.
2
Deoxyribonucleic Acid Heterogeneity Between Human and Murine Strains of Chlamydia trachomatis.沙眼衣原体人源和鼠源株间的脱氧核糖核酸异质性。
Infect Immun. 1970 Jul;2(1):24-8. doi: 10.1128/iai.2.1.24-28.1970.
3
OCCURENCE OF GLYCOGEN IN INCLUSIONS OF THE PSITTACOSIS-LYMPHOGRANULOMA VENEREUM-TRACHOMA AGENTS.鹦鹉热-性病性淋巴肉芽肿-沙眼病原体包涵体中糖原的出现情况。
J Infect Dis. 1965 Apr;115:186-96. doi: 10.1093/infdis/115.2.186.
4
Analysis of the immune response in mice following intrauterine infection with the Chlamydia trachomatis mouse pneumonitis biovar.沙眼衣原体小鼠肺炎生物变种宫内感染后小鼠免疫反应的分析
Infect Immun. 1993 Feb;61(2):772-6. doi: 10.1128/iai.61.2.772-776.1993.
5
Phylogenetic analysis of the outer-membrane-protein genes of Chlamydiae, and its implication for vaccine development.衣原体外膜蛋白基因的系统发育分析及其对疫苗开发的意义。
Mol Biol Evol. 1993 Jul;10(4):892-913. doi: 10.1093/oxfordjournals.molbev.a040048.
6
A new animal model for the study of Chlamydia trachomatis genital infections: infection of mice with the agent of mouse pneumonitis.一种用于研究沙眼衣原体生殖道感染的新动物模型：用小鼠肺炎病原体感染小鼠。
J Infect Dis. 1981 Jan;143(1):63-6. doi: 10.1093/infdis/143.1.63.
7
Incidence, prevalence, and trends of acute pelvic inflammatory disease and its consequences in industrialized countries.工业化国家急性盆腔炎及其后果的发病率、患病率和趋势。
Am J Obstet Gynecol. 1980 Dec 1;138(7 Pt 2):880-92. doi: 10.1016/0002-9378(80)91077-7.
8
Immune response in mice infected in the genital tract with mouse pneumonitis agent (Chlamydia trachomatis biovar).小鼠生殖道感染小鼠肺炎病原体（沙眼衣原体生物变种）后的免疫反应。
Infect Immun. 1984 Apr;44(1):82-5. doi: 10.1128/iai.44.1.82-85.1984.
9
Chlamydia trachomatis-induced salpingitis in mice.沙眼衣原体诱导的小鼠输卵管炎
J Infect Dis. 1983 Dec;148(6):1101-7. doi: 10.1093/infdis/148.6.1101.
10
Establishment of genital tract infection in the CF-1 mouse by intravaginal inoculation of a human oculogenital isolate of Chlamydia trachomatis.通过阴道接种沙眼衣原体人眼生殖器分离株在CF-1小鼠中建立生殖道感染。
J Infect Dis. 1984 Oct;150(4):577-82. doi: 10.1093/infdis/150.4.577.

用沙眼衣原体小鼠肺炎生物变种对小鼠进行阴道内接种会导致不育。

Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility.

作者信息

de la Maza L M, Pal S, Khamesipour A, Peterson E M

机构信息

Department of Pathology, University of California, Irvine 92717-4800.

出版信息

Infect Immun. 1994 May;62(5):2094-7. doi: 10.1128/iai.62.5.2094-2097.1994.

DOI:10.1128/iai.62.5.2094-2097.1994
PMID:8168974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC186471/
Abstract

In an attempt to establish a model of chlamydial ascending salpingitis and infertility, three inbred strains of mice, C3H/HeN (H-2k), C57BL/6N (H-2b), and BALB/cAnN (H-2d), were inoculated intravaginally with 3 x 10(7) inclusion-forming units of the Chlamydia trachomatis mouse pneumonitis biovar. Mice mated 6 weeks following inoculation were found to have a significant decrease in fertility rate compared with the control groups, as shown by a reduction in the number of pregnant mice and a decrease in the number of embryos.

摘要

为建立衣原体上行性输卵管炎和不孕症模型，将3×10⁷个沙眼衣原体小鼠肺炎生物变种的包涵体形成单位经阴道接种到三种近交系小鼠，即C3H/HeN（H-2k）、C57BL/6N（H-2b）和BALB/cAnN（H-2d）体内。接种6周后交配的小鼠与对照组相比，生育率显著降低，表现为怀孕小鼠数量减少和胚胎数量减少。