实验性充血性脾肿大：大鼠的组织学观察
Experimental congestive splenomegaly: histological observations in the rat.
作者信息
Manenti A, Botticelli A, Gibertini G, Botticelli L
机构信息
Cattedra di Patologia speciale Chirurgica, Università di Modena.
出版信息
Pathologica. 1993 Nov-Dec;85(1100):721-4.
PMID:8170720
Abstract
In course of experimental pre-hepatic portal hypertension in the rat, the most important histological alterations in the spleen, are represented by pooling of blood in the red pulp, activation of the macrophagic system, with hyperplasia of the histiocytes, increase of reticular fibers and of subcapsular myo-fibroblasts, and finally by evolution towards a diffuse fibrosis all over the parenchyma.
摘要
在大鼠实验性肝前门静脉高压形成过程中，脾脏最重要的组织学改变表现为红髓内血液淤积、巨噬细胞系统激活，伴有组织细胞增生、网状纤维和包膜下肌成纤维细胞增多，最终发展为整个实质的弥漫性纤维化。
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