[The clinical application of allergen-specific and total IgE determination in pediatric allergology (author's transl)].

Allergen specific IgE determination (Radio-Allergen-Sorbens-Test) were carried out on 150 patients 2 to 14 years old. The agreement with classical skin tests (Prick and intracutaneous tests) was for pollen allergies 87%, for allergies against house-dust and house-dust mites 80% and for allergies against animal denders 69%. There was however no agreement for allergies against molds (only 11%). The total IgE was measured in 51 children by radial immunodiffusion, pathologically high levels were found in 45% of patients. Allergen-specific IgE determinations (RAST) seem to be especially useful for young allergic children.