Tang R B, Wu K K
Department of Pediatrics, Veterans General Hospital, Taipei, Taiwan, Republic of China.
Ann Allergy. 1989 May;62(5):432-5.
Correlations of total serum IgE, skin test reactivity, and specific IgE antibodies to selected antigens were evaluated in asthmatic children. There was a significant difference in mean IgE level of each positive RAST score group compared with that of the RAST-negative score for dog epithelium, Candida, ragweed, and Bermuda grass allergen. The correlation coefficient between the total IgE and the RAST to D. farinae was 0.39 (P less than .05). There was no significant correlation between the total IgE and the RAST to D. pteronyssinus, Candida, dog epithelium, ragweed, Eucalyptus pollen, and Bermuda grass (P greater than .05). This indicates a low total serum IgE concentration does not exclude the possibility of significant elevation of specific IgE to a common allergen. Concordance for results of intradermal skin testing and RAST was high for most allergens. Lower efficiency for dog allergen and Candida suggests greater sensitivity of allergy skin testing for these allergens.
对哮喘儿童血清总IgE、皮肤试验反应性以及针对特定抗原的特异性IgE抗体之间的相关性进行了评估。与犬上皮、念珠菌、豚草和百慕大草过敏原的RAST阴性评分组相比，每个阳性RAST评分组的平均IgE水平存在显著差异。总IgE与粉尘螨RAST之间的相关系数为0.39（P<0.05）。总IgE与屋尘螨、念珠菌、犬上皮、豚草、桉属花粉和百慕大草的RAST之间无显著相关性（P>0.05）。这表明血清总IgE浓度较低并不排除针对常见过敏原的特异性IgE显著升高的可能性。大多数过敏原的皮内皮肤试验和RAST结果一致性较高。犬过敏原和念珠菌的效率较低，表明过敏皮肤试验对这些过敏原的敏感性更高。
