Dana F, Becherer P R, Bacon B R
Department of radiology, University of Florida Health Sciences Center, Jacksonville.
Postgrad Med. 1994 May 1;95(6):121-2, 125-30.
Hepatitis C virus (HCV) is responsible for most cases of non-A non-B hepatitis and is primarily spread by a parenteral route, although familial, sexual, and maternal transmission may occur rarely. Second-generation assays and the polymerase chain reaction facilitate detection of HCV infection. The association between HCV infection and hepatocellular cancer is well established, whereas the links between HCV infection and essential mixed cryoglobulinemia, porphyria cutanea tarda, membranoproliferative glomerulonephritis, and idiopathic pulmonary fibrosis remain to be defined more clearly. Standard therapy for chronic HCV infection remains interferon alfa-2b (Intron A), although other agents may have potential. We eagerly await additional clarifying studies.
丙型肝炎病毒（HCV）是大多数非甲非乙型肝炎病例的病因，主要通过肠道外途径传播，不过家族性、性传播和母婴传播可能很少发生。第二代检测方法和聚合酶链反应有助于丙型肝炎病毒感染的检测。丙型肝炎病毒感染与肝细胞癌之间的关联已得到充分证实，而丙型肝炎病毒感染与原发性混合性冷球蛋白血症、迟发性皮肤卟啉症、膜增生性肾小球肾炎和特发性肺纤维化之间的联系仍有待更明确地界定。慢性丙型肝炎病毒感染的标准治疗仍然是干扰素α-2b（干扰能），尽管其他药物可能具有潜力。我们热切期待更多的澄清性研究。
