Brevinge H, Jacobsson L
Dept. of Surgery and Radiation Physics, University of Göteborg, Sweden.
Scand J Gastroenterol. 1994 Feb;29(2):160-5. doi: 10.3109/00365529409090456.
Decreased exchangeable body sodium might be a consequence of proctocolectomy and construction of an ileal reservoir. To investigate this, 35 patients with ulcerative colitis and conventional ileostomy were studied before and after conversion to continent ileostomy and compared with 25 unoperated subjects as reference. The sodium urinary excretion varied between 7 and 229 and 1 and 217 mmol/24 h in patients with conventional and reservoir ileostomy, respectively. The total exchangeable sodium was measured and related to body composition estimated from body weight, total body water, and total body potassium. No effect on exchangeable sodium was observed after conversion: 3100 mmol and 2990 mmol, respectively. Patients with ileostomy, regardless of type, did not differ from reference subjects in their exchangeable sodium when related to total body water. A larger variation of total exchangeable sodium related to total body water suggests unstable sodium homeostasis in patients with ileal reservoir compared with reference subjects.
可交换体钠减少可能是直肠结肠切除术和回肠储袋构建的结果。为了对此进行研究，对35例溃疡性结肠炎并采用传统回肠造口术的患者在转换为可控性回肠造口术之前和之后进行了研究，并与25名未接受手术的受试者作为对照。传统回肠造口术和储袋回肠造口术患者的尿钠排泄量分别在7至229 mmol/24小时和1至217 mmol/24小时之间。测量了总可交换钠，并将其与根据体重、总体水和总体钾估算的身体成分相关联。转换后未观察到对可交换钠的影响：分别为3100 mmol和2990 mmol。无论何种类型，回肠造口术患者的可交换钠与总体水相关时与对照受试者并无差异。与对照受试者相比，总可交换钠与总体水的较大差异表明回肠储袋患者的钠稳态不稳定。
