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[慢性应激、长期低氧适应及其联合作用对不同类型特征大鼠行为的影响]

[The effect of chronic stress, long-term adaptation to hypoxia and their combination on the behavior of rats with different typological characteristics].

作者信息

Livanova L M, Levshina I P, Kurochkina E V

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 1994 Jan-Feb;44(1):75-9.

PMID:8171907
Abstract

Chronic stress caused by 3-week electro-pain stimulation (4 h daily) combined with "white noise", resulted in a decrease of horizontal motor activity of rats with extreme types of behaviour, i.e., active and passive. No changes in behaviour of animals with intermediate behavioural type were found. Long-term (30 days) adaptation to hypoxia (daily lifting to 11,000 m for 5 h) did not cause changes in behaviour of rats. Combination of stress and hypoxia caused an increase of number of grooming acts in rats with passive type of behaviour, testifying to their increased anxiety. Long-term adaptation to hypoxia did not influence the degree of loss of motor activity caused by chronic stress in animals with active and passive types of behaviour.

摘要

为期3周的电疼痛刺激(每日4小时)与“白噪声”相结合所引发的慢性应激,导致具有极端行为类型(即活跃型和被动型)的大鼠水平运动活动减少。未发现具有中间行为类型的动物行为有变化。长期(30天)缺氧适应(每日升至11000米并持续5小时)未引起大鼠行为改变。应激与缺氧相结合导致被动行为类型的大鼠梳理行为次数增加,证明其焦虑加剧。长期缺氧适应并未影响活跃型和被动型行为动物因慢性应激而导致的运动活动丧失程度。

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