Valkila E H, Salenius J P, Koivula T A
Department of Clinical Chemistry, Tampere University Hospital, Finland.
Angiology. 1994 May;45(5):361-5. doi: 10.1177/000331979404500505.
During the period 1965-1984 a total of 279 patients underwent carotid endarterectomy at the Tampere University Hospital; 160 of them were reexamined twenty-eight to two hundred nine months later to investigate whether there are any long-term differences in platelet properties according to the endpoint that led to operation. Platelet count, mean platelet volume (MPV), and plateletcrit were estimated and compared with the respective values for controls. Classified according to the indication for operation, patients with stroke had a significantly higher platelet count, 292 x 10(9)/L (SE 11), than patients with transient ischemic attack (TIA), 255 x 10(9)/L (SE 5, p < 0.01), or controls, 267 x 10(9)/L (SE 6, p < 0.05). Patients with stroke or TIA had a higher MPV than the controls. When the patients were grouped according to their physical condition at the time of the control examination, the largest platelets, 10.84 x 10(-15) L (SE 0.40), were found in the group of patients who felt well but who had a symptom or finding assumed to be due to a carotid disease.
1965年至1984年期间，共有279例患者在坦佩雷大学医院接受了颈动脉内膜切除术；其中160例在28至209个月后接受复查，以调查根据导致手术的终点，血小板特性是否存在任何长期差异。估计了血小板计数、平均血小板体积（MPV）和血小板压积，并与对照组的相应值进行比较。根据手术指征分类，中风患者的血小板计数显著高于短暂性脑缺血发作（TIA）患者[292×10⁹/L（标准误11）对255×10⁹/L（标准误5，p<0.01）]或对照组[267×10⁹/L（标准误6，p<0.05）]。中风或TIA患者的MPV高于对照组。当根据对照检查时的身体状况对患者进行分组时，在感觉良好但有症状或发现被认为是由颈动脉疾病引起的患者组中发现了最大的血小板[10.84×10⁻¹⁵L（标准误0.40）]。
