Chavaz A, Mignon F, Kanfer A, Richet G
Nouv Presse Med. 1976 Feb 28;5(9):565-9.
A report of the treatment by repeated dialysis of irreversible renal failure complicating 4 cases of multiple myeloma. The latter condition continued to progress, with death occurring after three, six, eight and twenty seven months. The last case was the only one with an indiscutable haematological and clinical remission. The effectiveness of chemotherapy is the reason for the use of the artifical kidney. Treatment may be hoped to be active if the renal failure is acute, a presenting feature of the myeloma. Such a hope is practically vain if the renal failure develops progressively, in a patient already on treatment. The indication for haemodialysis is thus more than open to discussion.
4例多发性骨髓瘤合并不可逆肾衰竭的重复透析治疗报告。后一种情况持续进展,分别于3个月、6个月、8个月和27个月后死亡。最后1例是唯一有明确血液学和临床缓解的病例。化疗的有效性是使用人工肾的原因。如果肾衰竭是急性的,作为骨髓瘤的一个表现特征,有望进行积极治疗。但如果肾衰竭在已接受治疗的患者中逐渐发展,这种希望实际上是徒劳的。因此,血液透析的适应证极具争议。