Hall R R
Freeman Hospital, High Heaton, Newcastle upon Tyne.
BMJ. 1994 Apr 2;308(6933):910-3. doi: 10.1136/bmj.308.6933.910.
Bladder cancer is almost certainly a product of the industrial revolution and the cigarette smoking that has accompanied it. Exposure to a chemical bladder carcinogen such as beta naphthylamine, benzidine, or 4-diphenylaniline can be proved in only a small proportion of patients and only a handful obtain industrial diseases benefit after developing "Prescribed Industrial Disease C23." None the less, the continued use of known carcinogenic substances in British industry for many years after their identification, the wide range of industries with a known or suspected increased risk of bladder cancer, and our ignorance of the carcinogenic potential of many materials used in current manufacturing should be a cause for continuing concern.
膀胱癌几乎可以肯定是工业革命及其伴随的吸烟的产物。仅在一小部分患者中能够证明接触过化学性膀胱致癌物，如β-萘胺、联苯胺或4-二苯胺，并且只有少数人在患上“规定的职业病C23”后获得了职业病福利。尽管如此，在已知致癌物质被识别后的许多年里，它们仍在英国工业中持续使用，众多已知或疑似膀胱癌风险增加的行业，以及我们对当前制造业中使用的许多材料的致癌潜力的无知，都应持续引发关注。
