Sharp C W, Clark S A, Dunan J R, Blackwood D H, Shapiro C M
University of Edinburgh, Department of Psychiatry, Royal Edinburgh Hospital, Morningside Park.
Int J Eat Disord. 1994 Mar;15(2):125-34. doi: 10.1002/1098-108x(199403)15:2<125::aid-eat2260150204>3.0.co;2-o.
As part of a larger prognostic study of anorexia nervosa, clinical features at presentation of 24 males with anorexia are described, and compared with a female group matched for date of admission. Data were extracted from the original case records and follow-up interview. The study confirms the view that males display the classical syndrome of anorexia nervosa, but differs from previous studies in several respects. Age at onset (mean 18.6 years) and at presentation (mean 20.2 years) is later, with a mean duration of illness at presentation of only 1.6 years. A premorbid tendency to obesity is confirmed; maximum weight loss during the illness amounted to 42% matched population mean weight (MPMW), and weight at presentation was 78.5% MPMW, somewhat higher than the female group. In keeping with earlier studies, binging and vomiting were noted commonly, in around half of sufferers, but laxative abuse was less frequent and excessive exercising more frequent in males. Depressive and obsessional symptoms are common in both groups, and a strong family history of affective disorders and alcohol abuse was noted in over one third.
作为一项关于神经性厌食症的大型预后研究的一部分，本文描述了24名男性神经性厌食症患者就诊时的临床特征，并与一组按入院日期匹配的女性患者进行了比较。数据取自原始病例记录和随访访谈。该研究证实了男性会表现出神经性厌食症的典型综合征这一观点，但在几个方面与先前的研究有所不同。发病年龄（平均18.6岁）和就诊年龄（平均20.2岁）较晚，就诊时的平均病程仅为1.6年。病前肥胖倾向得到证实；患病期间最大体重减轻达匹配人群平均体重（MPMW）的42%，就诊时体重为MPMW的78.5%，略高于女性组。与早期研究一致，约一半患者常有暴饮暴食和呕吐现象，但男性滥用泻药情况较少，过度运动情况较多。抑郁和强迫症状在两组中都很常见，超过三分之一的患者有情感障碍和酒精滥用的强烈家族史。
