Svitac J, Kliment J, Lepej J, Fetisov I
Urologická klinika LFUK a FNsP, Martin, Slovakia.
Bratisl Lek Listy. 1993 May;94(5):278-81.
The method of diuretic scintigraphy was used to examine 27 children, aged 2-15 years, with excretion urography findings of dilatation of the upper urinary tract. Vesicorenal reflux was excluded in all the children of the series by classical radiologic cystography. The radionuclide 131I-hippurate was used in 15 children and 99mTc-MAG3 in 12 children. In both groups the parameter T 1/2 was determined as the time of 50% decrease of activity above the kidney after administration of the diuretic. With both radionuclides the same borderline time of T 1/2 was established. In cases with T 1/2 < 10 minutes and preserved kidney function, dilatation of obstructive origin can be excluded with both substances. 99mTc-MAG3, however, has a markedly better imaging capacity and a significantly lower radiation load than 131I-hippurate. (Tab. 4, Fig. 3, Ref. 12.)
采用利尿肾动态显像法对27例2至15岁、排泄性尿路造影显示上尿路扩张的儿童进行检查。通过经典放射学膀胱造影排除了该系列所有儿童的膀胱输尿管反流。15例儿童使用放射性核素131I - 马尿酸盐，12例儿童使用99mTc - MAG3。在两组中，参数T 1/2被确定为给予利尿剂后肾上方活性降低50%的时间。使用两种放射性核素时，T 1/2的临界时间相同。在T 1/2 < 10分钟且肾功能正常的情况下，两种物质均可排除梗阻性扩张。然而，99mTc - MAG3的显像能力明显优于131I - 马尿酸盐，且辐射剂量显著更低。（表4，图3，参考文献12）
