Chern J H, Chen C H, Lee Y C, Chern M S, Perng R P
Chest Department, Veterans General Hospital-Taipei, Taiwan, R.O.C.
Zhonghua Yi Xue Za Zhi (Taipei). 1994 Mar;53(3):179-84.
Allergic bronchopulmonary aspergillosis (ABPA), an uncommon but potentially destructive Aspergillus-associated pulmonary disease, is characterized by recurrent episodes of pulmonary infiltration and central bronchiectasis in patients with pre-existing asthma. It is important but difficult to find out ABPA from asthmatic patients because ABPA may lead to irreversible pulmonary fibrosis and there are much overlap in the clinical and laboratory findings between ABPA and asthma. However, once identified and treated early, patients with ABPA may respond well and the evolution to the end stage may be prevented. Here we report three documented cases of ABPA. One of them had no history of asthma but had the history of allergy to cosmetics. All three cases were suspected by the typical roentgenographic finding ("toothpaste" shadows) and were treated by short course of prednisolone with satisfactory clinical improvement.
变应性支气管肺曲霉病（ABPA）是一种罕见但可能具有破坏性的曲霉相关性肺部疾病，其特征为在已有哮喘的患者中反复出现肺部浸润和中心性支气管扩张。从哮喘患者中找出ABPA很重要但也很困难，因为ABPA可能导致不可逆的肺纤维化，且ABPA与哮喘在临床和实验室检查结果上有很多重叠之处。然而，一旦早期识别并治疗，ABPA患者可能反应良好，并可预防发展至终末期。在此我们报告3例确诊的ABPA病例。其中1例无哮喘病史，但有化妆品过敏史。所有3例均通过典型的X线表现（“牙膏”影）怀疑，并接受了短疗程泼尼松龙治疗，临床改善满意。
