Waga S, Handa H
Surg Neurol. 1976 Apr;5(4):215-9.
A case of tentorial meningioma occurring 12 years after radiation therapy for a verified craniopharyngioma is presented. The pertinent literature is reviewed and it is concluded that irradiation of the brain may be responsible for the late development of intracranial meningiomas, which are less common, however, than sarcomas. A long survival after irradiation, "misregeneration" in the chronic inflammatory processes induced by irradiation, and an immunodeficiency caused by irradiation and other factors, may play some role in developing oncogenesis.
本文报告1例在确诊颅咽管瘤放射治疗12年后发生的小脑幕脑膜瘤病例。回顾相关文献后得出结论,脑部放疗可能是颅内脑膜瘤晚期发生的原因,不过颅内脑膜瘤比肉瘤少见。放疗后的长期存活、放疗诱导的慢性炎症过程中的“错误再生”以及放疗和其他因素引起的免疫缺陷,可能在肿瘤发生过程中起一定作用。