Zenke K, Fukumoto S, Ohta S, Sakaki S, Matsui S
Department of Neurosurgery, Ehime University Medical School.
No Shinkei Geka. 1993 Sep;21(9):829-32.
We presented a case of secondary giant meningioma with dense calcification (brain stone) after radiation therapy for primary ependymoma removed 25 years before. A 31-year-old man was referred to our hospital because of generalized convulsion. He had received extirpation of an ependymoma in the left frontoparietal region and postoperative radiation therapy 25 years before. Skull X-ray and CT revealed a giant brain stone in the left parietal region. It was totally removed en bloc. Photomicrograph of the specimen showed proliferation of arachnoid cell-like tumor cells in narrow spaces surrounded by marked calcified lesions which showed partial ossification. The etiology and therapy of this tumor were discussed.
我们报告了一例继发于25年前接受放射治疗的原发性室管膜瘤切除术后的伴有致密钙化（脑石）的巨大脑膜瘤病例。一名31岁男性因全身性惊厥被转诊至我院。他在25年前接受了左额顶叶室管膜瘤切除术及术后放射治疗。头颅X线和CT显示左顶叶有一个巨大脑石。肿瘤被完整切除。标本的显微照片显示，在被明显钙化病变（部分呈骨化）包围的狭窄间隙中，蛛网膜样肿瘤细胞增生。本文对该肿瘤的病因及治疗进行了讨论。
