Bodin I K, Lind M G, Arnander C
Department of Oral and Jaw Disease, Karolinska Hospital, Sweden.
Clin Otolaryngol Allied Sci. 1994 Feb;19(1):28-34. doi: 10.1111/j.1365-2273.1994.tb01143.x.
The first 100 consecutive free radial forearm flaps used in reconstruction for oral and pharyngeal cancer were investigated. Seven re-operations took place due to circulatory impairment of the flap. Two flaps underwent partial, and four total necrosis, one of those patients died of massive haemorrhage. Post-operative infection was significantly correlated to increased time between the last radiotherapy session and surgery. All but eight patients had post-operative impairment of swallowing and all but five patients had impairment of speech articulation or hypernasality. Post-operative time spent in hospital was a range of 12-122 days (mean 37 days). The 2-year survival rate was 70% and the 5-year survival rate was 45%.
对首批连续100例用于口腔和咽癌重建的游离桡侧前臂皮瓣进行了研究。因皮瓣循环障碍进行了7次再次手术。2例皮瓣部分坏死,4例完全坏死,其中1例患者死于大出血。术后感染与最后一次放疗疗程至手术之间的时间延长显著相关。除8名患者外,所有患者均有吞咽功能障碍,除5名患者外,所有患者均有言语清晰度受损或鼻音过重的问题。术后住院时间为12 - 122天(平均37天)。2年生存率为70%,5年生存率为45%。