Fishman A, Girtanner R E, Adam E, Kaufman R H, Kaplan A L
Department of Obstetrics/Gynecology, Baylor College of Medicine, Houston, Texas 77030.
Gynecol Oncol. 1994 Apr;53(1):128-30. doi: 10.1006/gyno.1994.1101.
Myocutaneous flaps have been used for vulvar reconstruction following radical vulvectomy. For over 15 years the most common complications related to these flaps are sloughing of the skin and donor site wound infection. A new malignancy arising from the skin of the neovulva is an unusual occurrence. Two cases are presented. The skin of the neovulva may be exposed to the same neoplastic carcinogens that caused the initial lesion. In both patients, the polymerase chain reaction method failed to detect the presence of human papillomavirus DNA in either the initial lesion or the recurrent cancer.
肌皮瓣已被用于根治性外阴切除术后的外阴重建。在过去15年多的时间里，与这些皮瓣相关的最常见并发症是皮肤脱落和供区伤口感染。新外阴皮肤出现新的恶性肿瘤是一种罕见的情况。本文介绍两例病例。新外阴的皮肤可能暴露于导致初始病变的相同致癌物质中。在这两名患者中，聚合酶链反应方法未能在初始病变或复发性癌症中检测到人乳头瘤病毒DNA的存在。
