Interictal--ictal transition in the feline penicillin epileptogenic focus.

A study was undertaken to examine those EEG features which characterize interictal--ictal (II--I) transitions in the feline penicillin focus. The study describes certain complex changes in spike frequency and their statistical analysis, which appear to have predictive value in signaling II--I transitions. The significance of these data with respect to the conflicting results of other studies and their possible application to clinical epilepsy are discussed.