Nadkarni S R, Patel M V, Chatterjee S, Vijayakumar E K, Desikan K R, Blumbach J, Ganguli B N, Limbert M
Microbiology Department, Hoechst India Limited, Mulund (W), Bombay.
J Antibiot (Tokyo). 1994 Mar;47(3):334-41. doi: 10.7164/antibiotics.47.334.
A new glycopeptide antibiotic, balhimycin, has been isolated from the fermentation broth of a Amycolatopsis sp. Y-86,21022. Balhimycin belongs to the vancomycin class of glycopeptides and contains a dehydrovancosamine sugar. The biological activity of balhimycin has been compared extensively with that of vancomycin against methicillin resistant staphylococci and also against anaerobes. Balhimycin is marginally superior to vancomycin in its in vitro activity against anaerobes and in its bactericidal properties.
一种新的糖肽类抗生素——巴利霉素，已从一株拟无枝酸菌属菌株Y - 86,21022的发酵液中分离出来。巴利霉素属于糖肽类的万古霉素家族，含有去氢万古糖胺糖。巴利霉素与万古霉素针对耐甲氧西林葡萄球菌以及厌氧菌的生物活性已被广泛比较。在体外对厌氧菌的活性及其杀菌特性方面，巴利霉素略优于万古霉素。
