Jensen I
Acta Neurol Scand. 1976 May;53(5):335-57. doi: 10.1111/j.1600-0404.1976.tb04353.x.
Types of seizures, age at onset of epilepsy, preoperative duration of epilepsy, and age at operation were studied in the literature and in 74 patients who underwent unilateral temporal lobe resection in 1960-1969 in Denmark. The medical and surgical series were compared. The age at onset was significantly lower in the surgical series. Prognostically favourable factors were: i) preoperative presence of a single type of seizure; ii) duration of epilepsy of less than 4 years, and in grand mal epilepsy of less than 1 year; iii) operation for epilepsy in or before early adulthood. Prognostically unfavourable factors were i) preoperative presence of grand mal; ii) age at onset of epilepsy or of the first grand mal seizure between 5 and 20 years; iii) preoperative duration of psychomotor epilepsy over 10 years.
我们在文献以及1960年至1969年期间在丹麦接受单侧颞叶切除术的74例患者中,研究了癫痫发作类型、癫痫起病年龄、术前癫痫持续时间以及手术年龄。对医疗和手术病例系列进行了比较。手术病例系列的起病年龄显著更低。预后良好的因素为:i)术前存在单一类型的癫痫发作;ii)癫痫持续时间少于4年,大发作癫痫少于1年;iii)在成年早期或成年早期之前进行癫痫手术。预后不良的因素为:i)术前存在大发作;ii)癫痫起病年龄或首次大发作癫痫发作年龄在5至20岁之间;iii)术前精神运动性癫痫持续时间超过10年。