神经毒性霉菌毒素：对引起大型动物神经疾病的真菌毒素的综述

Neurotoxic mycotoxins: a review of fungal toxins that cause neurological disease in large animals.

作者信息

Plumlee K H, Galey F D

机构信息

Department of Toxicology, California Veterinary Diagnostic Laboratory Systems, Davis 95617-1770.

出版信息

J Vet Intern Med. 1994 Jan-Feb;8(1):49-54. doi: 10.1111/j.1939-1676.1994.tb03195.x.

DOI:10.1111/j.1939-1676.1994.tb03195.x

PMID:8176663

Abstract

Five mycotoxins found in concentrates or roughages have been shown to cause neurologic disease in livestock. Fumonisin B1 is produced by Fusarium moniliforme and causes leukoencephalomalacia in horses. Swainsonine and slaframine are produced by Rhizoctonia leguminicola and cause mannose accumulation and parasympathomimetic effects, respectively. Lolitrems from Acremonium lolii and paspalitrems from Claviceps paspali are tremorgens found in grasses.

摘要

已证实，在精饲料或粗饲料中发现的五种霉菌毒素可导致家畜出现神经疾病。伏马菌素B1由串珠镰刀菌产生，可导致马患白质软化症。苦马豆素和莱克多巴胺分别由豆科丝核菌产生，可导致甘露糖积累和拟副交感神经效应。来自黑麦草内生真菌的黑麦草毒素和来自雀稗麦角菌的雀稗麦角碱是在牧草中发现的震颤毒素。