Rubio C, Shetye J, Jaramillo E
Department of Pathology, Karolinska Hospital, Stockholm, Sweden.
J Surg Oncol. 1994 May;56(1):59-62. doi: 10.1002/jso.2930560114.
It has been claimed that in order to identify the type of mucosal lesion which precedes colonic adenocarcinoma only those tumours measuring < or = 1 mm in diameter should be considered. The review of the English literature indicates that only 35 colorectal adenocarcinomas measuring < or = 1 cm in diameter have been so far reported. From the three cases of colonic adenocarcinoma measuring 8 mm or less in diameter presented here, one adenocarcinoma originated in a flat adenoma, the second in an exophytic tubular adenoma, and the third showed no adenomatous component. It would thus appear that colonic adenocarcinomas can originate not only from exophytic adenomas or from flat adenomas but also from apparently nonadenomatous flat mucosa.
有人声称，为了确定结肠腺癌之前的黏膜病变类型，仅应考虑那些直径小于或等于1毫米的肿瘤。对英文文献的综述表明，迄今为止仅报道了35例直径小于或等于1厘米的结直肠癌。从这里展示的3例直径为8毫米或更小的结肠腺癌病例来看，1例腺癌起源于扁平腺瘤，第2例起源于外生性管状腺瘤，第3例未显示腺瘤成分。因此，结肠腺癌似乎不仅可起源于外生性腺瘤或扁平腺瘤，还可起源于明显无腺瘤的扁平黏膜。
