Rubio C A, Kato Y, Hirota T, Muto T
Department of Pathology, Gastrointestinal Pathology Research Laboratory, Karolinska Institute, Stockholm, Sweden.
Jpn J Cancer Res. 1996 Aug;87(8):849-55. doi: 10.1111/j.1349-7006.1996.tb02110.x.
A total of 594 flat colorectal polyps, removed at endoscopy, were histologically classified into non-neoplastic (n = 49) and neoplastic (n = 545) polyps. Non-neoplastic polyps were subdivided into metaplastic (n = 45) and hyperplastic (n = 4), whereas neoplastic polyps were subdivided into adenomas (n = 481), intramucosal carcinomas (n = 28) and invasive adenocarcinomas (n = 36). Several adenoma phenotypes were discerned: tubular (n = 375), serrated (n = 59), villous (n = 39), mixed (n = 7) and fenestrated (n = 1). Intramucosal carcinomas were subdivided into tubular (n = 26) and serrated (n = 2), and invasive adenocarcinomas into tubular (n = 32), serrated (n = 3) and fenestrated (n = 1). The microscopic characteristics of each histologic phenotype described in this communication are defined and illustrated.
在内镜检查中切除的总共594个扁平结直肠息肉,经组织学分类为非肿瘤性息肉(n = 49)和肿瘤性息肉(n = 545)。非肿瘤性息肉又细分为化生息肉(n = 45)和增生性息肉(n = 4),而肿瘤性息肉则细分为腺瘤(n = 481)、黏膜内癌(n = 28)和浸润性腺癌(n = 36)。辨别出几种腺瘤表型:管状腺瘤(n = 375)、锯齿状腺瘤(n = 59)、绒毛状腺瘤(n = 39)、混合性腺瘤(n = 7)和有窗孔性腺瘤(n = 1)。黏膜内癌细分为管状(n = 26)和锯齿状(n = 2),浸润性腺癌细分为管状(n = 32)、锯齿状(n = 3)和有窗孔性(n = 1)。本报告中描述的每种组织学表型的微观特征均已明确并图示。