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[慢性高血压孕妇的胎儿生长情况]

[Fetal growth in pregnant women with chronic hypertension].

作者信息

Delmis J, Drazancić A, Ivanisević M, Pfeifer D, Ljubojević N

机构信息

Klinika za zenske bolesti i porode Medicinskog fakulteta u Zagrebu.

出版信息

Lijec Vjesn. 1993 Nov-Dec;115(11-12):329-35.

PMID:8176992
Abstract

This study represents a retrospective analysis of pregnancies with chronic arterial hypertension and their outcomes. The aim was to evaluate the influence of arterial hypertension on 101 essential and 109 cases of secondary hypertension in comparison to the control group consisting of 499 normotensive pregnancies. According to the obtained data, 27.7% of the women with chronic hypertension had proteinuria, 61% had bacteriuria and 58.6% had superimposed EPH gestosis. The occurrence of EPH gestosis among the controls was 5.6%, that is significantly less than in the experimental group (X2 = 282.8%; p < 0.001). The outcomes of pregnancies associated with chronic hypertension were: 19% preterm deliveries compared to the controls in which only 9.2% preterm deliveries occurred (X2 = 14.4; p < 0.001). Newborns from pregnancies with essential hypertension were significantly heavier, weighing 3177 +/- 734 g, than those from pregnancies with secondary hypertension, which weighted 2578 +/- 932 g. Perinatal mortality was higher in the study group and significantly higher in the pregnancies with associated secondary hypertension (30.3%) than in pregnancies associated with essential hypertension (15.8%).

摘要

本研究对慢性动脉高血压孕妇及其妊娠结局进行了回顾性分析。目的是评估动脉高血压对101例原发性高血压和109例继发性高血压孕妇的影响,并与由499例血压正常孕妇组成的对照组进行比较。根据所得数据,慢性高血压孕妇中27.7%有蛋白尿,61%有菌尿,58.6%并发子痫前期-子痫综合征(EPH)。对照组中EPH的发生率为5.6%,显著低于实验组(X2 = 282.8%;p < 0.001)。与慢性高血压相关的妊娠结局为:19%早产,而对照组中只有9.2%早产(X2 = 14.4;p < 0.001)。原发性高血压孕妇所生新生儿明显更重,体重为3177±734克,而继发性高血压孕妇所生新生儿体重为2578±932克。研究组围产期死亡率较高,继发性高血压相关妊娠的围产期死亡率(30.3%)显著高于原发性高血压相关妊娠(15.8%)。

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