Ogawa-Meguro R, Shigemoto R, Itoh K, Konishi A, Mizuno N
Department of Morphological Brain Science, Faculty of Medicine, Kyoto University, Japan.
Neurosci Lett. 1994 Jan 31;166(2):135-8. doi: 10.1016/0304-3940(94)90469-3.
The superficial layers of the superior colliculus (SC) have been known to contain many axons showing substance P-like immunoreactivity (SP-LI). We, therefore, immunohistochemically examined the distribution of SP receptor (SPR) in the superficial layers of the SC in the rat by using a specific antibody against SPR. The majority of SC neurons with SPR-LI were distributed in the zonal and the superficial gray layers, the rest of them were in the optic layer. Electron microscopy revealed that SPR-immunoreaction products in SC neurons were distributed not only in postsynaptic sites, but also in non-synaptic regions of perikaryal and dendritic profiles.
已知上丘（SC）的表层含有许多显示P物质样免疫反应性（SP-LI）的轴突。因此，我们通过使用针对SP受体（SPR）的特异性抗体，对大鼠SC表层中SPR的分布进行了免疫组织化学检查。大多数具有SPR-LI的SC神经元分布在带状层和表层灰质层，其余的分布在视层。电子显微镜显示，SC神经元中的SPR免疫反应产物不仅分布在突触后部位，还分布在胞体和树突轮廓的非突触区域。
