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淋病奈瑟菌的扫描电子显微镜观察。年龄诱导的有毒和无毒菌落宏观及微观结构变化。

Scanning electron microscopy of Neisseria gonorrhoeae. Age-induced changes in macro- and microstructure of virulent and avirulent colonies.

作者信息

Elmros T, Normark S, Sandström G, Winblad B

出版信息

Br J Vener Dis. 1976 Apr;52(2):136-41. doi: 10.1136/sti.52.2.136.

DOI:10.1136/sti.52.2.136
PMID:817778
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1045239/
Abstract

Virulent and avirulent gonococcal colonies were studied in the scanning electron microscope. Cells in virulent, in contrast to avirulent, colonies were found to be connected by numerous strands. After longer incubation periods, type 2 colonies segregated out regions of cells virtually lacking these strands. Cells within these areas probably represent avirulent segregants. The microstructure of individual colonies revealed no topographical differences. In certain colonies large smooth spherical cells were seen, probably representing wall-deficient gonococcal variants.

摘要

在扫描电子显微镜下研究了有毒力和无毒力的淋球菌菌落。与无毒力菌落相比，有毒力菌落中的细胞被发现通过大量细丝相连。培养较长时间后，2型菌落分离出几乎没有这些细丝的细胞区域。这些区域内的细胞可能代表无毒力的分离菌。单个菌落的微观结构没有显示出地形差异。在某些菌落中可见大的光滑球形细胞，可能代表细胞壁缺陷型淋球菌变体。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/c82b9382baec/brjvendis00050-0073-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/de780e180573/brjvendis00050-0069-a.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/042bbd7b9e2e/brjvendis00050-0069-c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/6e636a595753/brjvendis00050-0070-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/e2b8ab46abaa/brjvendis00050-0070-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/dac6b364d772/brjvendis00050-0071-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/20f3d4f88f56/brjvendis00050-0071-b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/20ac10bd9ddd/brjvendis00050-0072-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ae82/1045239/c82b9382baec/brjvendis00050-0073-a.jpg

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本文引用的文献

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DEVELOPMENT OF L-TYPE GROWTH IN NEISSERIA GONORRHOEAE CULTURES.淋病奈瑟菌培养物中L型生长的发展
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NEISSERIA GONORRHOEAE. I. VIRULENCE GENETICALLY LINKED TO CLONAL VARIATION.淋病奈瑟菌。一、与克隆变异基因连锁的毒力。
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Neisseria gonorrhoeae 3. Demonstration of presumed appendages to cells from different colony types.淋病奈瑟菌 3. 不同菌落类型细胞上假定附属物的展示。
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Dense cultures of Neisseria gonorrhoeae in liquid medium.淋病奈瑟菌在液体培养基中的密集培养物。
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Colonial morphology of Neisseria gonorrhoeae isolated from males and females.从男性和女性分离出的淋病奈瑟菌的菌落形态。
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Studies in venereal disease. I. Isolation of L-phase organisms of N. gonorrhoeae from patients with gonorrhoea.性病研究。一、从淋病患者中分离淋病奈瑟菌L型菌株。
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Characterization of plasmid deoxyribonucleic acid from Neisseria gonorrhoeae.淋病奈瑟菌质粒脱氧核糖核酸的特性分析。
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Factors affecting autolysis of Neisseria gonorrhoeae.影响淋病奈瑟菌自溶的因素。
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Induction and reversion of the L-form of Neisseria gonorrhoeae.
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