一名患有多种肿瘤的患者的免疫异常。
Immunologic abnormalities in a patient with multiple neoplasms.
作者信息
Ko H S, Minkarious E F
出版信息
Can Med Assoc J. 1976 May 22;114(10):917-9.
Abstract
Pernicious anemia, antithyroid antibodies, IgG(K) M component, depressed production of other immunoglobulins and impaired function of peripheral blood lymphocytes developed in a patient with adenocarcinoma of the colon, transitional-cell carcinoma of the tongue and clear-cell parathyroid adenoma. This case demonstrates that immunologic abnormalities and multiple malignant neoplasms may coexist in one patient. It lends support to the hypothesis that neoplastic processes and autoimmunity may both be related to impaired immune surveillance.
摘要
一名患有结肠癌、舌移行细胞癌和透明细胞甲状旁腺腺瘤的患者出现了恶性贫血、抗甲状腺抗体、IgG（K）M成分、其他免疫球蛋白产生减少以及外周血淋巴细胞功能受损的情况。该病例表明免疫异常和多种恶性肿瘤可能在同一患者中共存。这支持了肿瘤形成过程和自身免疫可能都与免疫监视受损有关的假说。
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