[高尿酸血症与痛风：治疗指征]
[Hyperuricemia and gout: therapeutic indications].
作者信息
Pawlotsky Y
机构信息
Service de rhumatologie, hôpital Sud, Rennes.
出版信息
Rev Prat. 1994 Jan 15;44(2):206-9.
Uricaemia-lowering treatment is indicated when hyperuricaemia is pronounced (90 mg/L or more) or when it is expressed by uric acid stones and/or gout. The drugs which lower plasma uric acid levels are presented according to their mode of action: uric acid inhibitors (allopurinol and tisopurine), uric acid excretors (probenecid, benzbromarone) and the uric acid lyser (urate-oxidase). The pharmacological and pharmaceutical data needed to understand the respective indications and applications of these drugs are given. These indications and those of adjuvant therapies are presented as answers to the following questions: when should a uricaemia-lowering treatment be initiated? What are the general rules to be obeyed? Which indications or contraindications must be borne in mind?
当高尿酸血症明显（90毫克/升或更高）或表现为尿酸结石和/或痛风时，需要进行降尿酸治疗。根据其作用方式介绍降低血浆尿酸水平的药物：尿酸抑制剂（别嘌醇和硫唑嘌呤）、尿酸排泄剂（丙磺舒、苯溴马隆）和尿酸溶解剂（尿酸氧化酶）。给出了理解这些药物各自适应证和应用所需的药理学和药学数据。这些适应证以及辅助治疗的适应证以回答以下问题的形式呈现：何时应开始降尿酸治疗？应遵循哪些一般规则？必须牢记哪些适应证或禁忌证？
Zotero 插件