Flechner S M
Department of Urology, Cleveland Clinic Foundation, Ohio.
Urol Clin North Am. 1994 May;21(2):265-82.
Renal transplantation is now well accepted as the preferred mode of renal replacement therapy for patients with end-stage renal disease. Recent advances in surgery, anesthesia, immunosuppression, and antimicrobial prophylaxis have made transplantation a more predictable clinical activity. The demand for kidneys has far outstripped the available supply in the United States, and careful selection and preparation of recipients is required to maximize the effective use of this limited resource. Newer immunosuppressive agents are on the horizon that offer promise for a further reduction in allograft rejection and decrease in post-transplant complications.
肾移植现已被广泛接受为终末期肾病患者肾脏替代治疗的首选方式。手术、麻醉、免疫抑制和抗菌预防方面的最新进展使移植成为一种更可预测的临床活动。在美国，对肾脏的需求远远超过了可获得的供应，因此需要仔细挑选和准备受者，以最大限度地有效利用这一有限资源。即将出现的新型免疫抑制剂有望进一步减少同种异体移植排斥反应，并降低移植后并发症的发生率。
