Albus M, Scherer J, Hueber S, Lechleuthner T, Kraus G, Zausinger S, Burkes S
State Mental Hospital Haar, Germany.
Acta Psychiatr Scand. 1994 Feb;89(2):132-4. doi: 10.1111/j.1600-0447.1994.tb01500.x.
To evaluate the impact of familial loading and gender on age at onset, 197 schizophrenic patients were investigated. Patients with familial loading had an earlier age at onset without gender differences. In contrast, an earlier age at onset for men was found in sporadic cases. These data support that both gender and familial loading contribute to the heterogeneity of schizophrenia.
为评估家族负荷和性别对发病年龄的影响,对197例精神分裂症患者进行了调查。有家族负荷的患者发病年龄较早,且无性别差异。相比之下,散发病例中男性发病年龄较早。这些数据支持性别和家族负荷均导致精神分裂症的异质性。