Fogarty F, Russell J M, Newman S C, Bland R C
Department of Psychiatry, University of Alberta, Edmonton, Canada.
Acta Psychiatr Scand Suppl. 1994;376:16-23.
3258 randomly selected household residents of Edmonton, Alberta were interviewed by trained lay interviewers using the Diagnostic Interview Schedule (DIS). The lifetime prevalence of mania was 0.6%, for both sexes combined. Lifetime morbidity risk was 1.4% for men and 0.6% for women. The mean age of onset was 20 years of age for both men and women. Ninety-five percent of bipolar individuals had had their first onset by age 26, and less than 5% had their onset before the age of 10. The mean number of manic episodes was 23. Comorbidity with other disorders occurred in 92% of the manic subjects. Depression (62%), alcohol abuse (45%), substance abuse (35%), and phobias (54%) had an increased lifetime prevalence in individuals with a history of a manic episode(s).
艾伯塔省埃德蒙顿市3258名随机抽取的家庭居民接受了训练有素的非专业访谈员使用诊断访谈表（DIS）进行的访谈。男女合并的躁狂症终生患病率为0.6%。男性终生发病风险为1.4%，女性为0.6%。男性和女性的平均发病年龄均为20岁。95%的双相情感障碍患者在26岁之前首次发病，不到5%的患者在10岁之前发病。躁狂发作的平均次数为2.3次。92%的躁狂症患者伴有其他疾病。有躁狂发作史的个体中，抑郁症（62%）、酒精滥用（45%）、药物滥用（35%）和恐惧症（54%）的终生患病率有所增加。
