Spaner D, Bland R C, Newman S C
Alberta Hospital, Edmonton, Canada.
Acta Psychiatr Scand Suppl. 1994;376:7-15.
A random sample of 3258 adult household residents of Edmonton, Alberta, Canada, were interviewed by trained lay interviewers, using the Diagnostic Interview Schedule (DIS), which generated DSM-III diagnosis data. This paper reports results for major depressive disorder (MDD). MDD was found to affect women more than men by a ratio of nearly 2 to 1. The lifetime prevalence rate for both sexes combined was 8.6%. The period prevalence rates for both sexes combined were 3.2% and 4.6%, for six month and one year, respectively. The presence of a recurrent Major Depressive Disorder was associated with an increased risk of substance abuse, panic disorder and dysthymia, whereas a single major depressive episode was not associated with increased comorbidity.
加拿大艾伯塔省埃德蒙顿市3258名成年家庭居民的随机样本，由经过培训的非专业访谈员使用诊断访谈表（DIS）进行访谈，该访谈表生成了《精神疾病诊断与统计手册》第三版（DSM - III）的诊断数据。本文报告了重度抑郁症（MDD）的研究结果。发现MDD对女性的影响大于男性，比例接近2比1。男女合并的终生患病率为8.6%。男女合并的六个月和一年期间患病率分别为3.2%和4.6%。复发性重度抑郁症的存在与物质滥用、惊恐障碍和心境恶劣障碍的风险增加相关，而单次重度抑郁发作与共病增加无关。
