铜绿假单胞菌烧伤创面感染与粒细胞抗菌活性之间的相关性。
Correlation between pseudomonas burn wound infection and granulocyte antibacterial activity.
作者信息
McEuen D D, Blair P, Delbene V E, Eurenius K
出版信息
Infect Immun. 1976 May;13(5):1360-2. doi: 10.1128/iai.13.5.1360-1362.1976.
The relationship of granulocyte bactericidal activity with three strains of pseudomonas and the virulence of these same organisms in a scald-burned rat model was investigated. Resistance to bactericidal activity was measured for each strain, using an in vitro assay and normal rat peritoneal granulocytes. Mortality was recorded for rats receiving a 30% third-degree scald burn with simultaneous pseudomonas burn wound infection. A positive correlation between mortality and resistance to bactericidal activity of granulocytes was obtained. These studies stress the importance of pseydomonas strain specificity in burn wound infection and indicate that mortality from these strains may be specifically related to their resistance to the bactericidal activity of leukocytes.
研究了粒细胞杀菌活性与三株假单胞菌的关系，以及这些相同菌株在烫伤大鼠模型中的毒力。使用体外测定法和正常大鼠腹腔粒细胞，测量了每株菌株对杀菌活性的抗性。记录了接受30%三度烫伤并同时伴有假单胞菌烧伤创面感染的大鼠的死亡率。获得了死亡率与粒细胞对杀菌活性的抗性之间的正相关关系。这些研究强调了假单胞菌菌株特异性在烧伤创面感染中的重要性，并表明这些菌株导致的死亡率可能与其对白细胞杀菌活性的抗性具体相关。
Zotero 插件