Williams S G, Westaby D
Department of Gastroenterology, Chelsea and Westminister Hospital, London.
BMJ. 1994 May 7;308(6938):1213-7. doi: 10.1136/bmj.308.6938.1213.
Fig 2 gives an algorithm for the treatment of bleeding oesophageal varices. Initial resuscitation of the patient is of paramount importance, ideally followed by early interventional endoscopy. Recent advances in available endoscopic techniques enable the endoscopist to suit the therapeutic approach to the clinical situation. Injection sclerotherapy remains the initial treatment of choice in bleeding patients. Endoscopic banding ligation is an alternative, best used in patients who have spontaneously stopped bleeding or as a complementary treatment a few days after the initial session of injection sclerotherapy. The tissue adhesives and thrombin can be used to treat bleeding gastric varices. [table: see text] Should the endoscopic expertise not be available, drug treatment (with somatostatin or octreotide) or balloon tamponade are the treatments of choice. Transjugular intrahepatic portal-systemic stent shunt is a new effective technique, not yet widely available, which has a documented complication rate that has yet to be fully defined. It is a good alternative to surgery as a "rescue" procedure for patients who continue to bleed despite two sessions of endoscopic intervention.
图2给出了食管静脉曲张出血的治疗算法。患者的初始复苏至关重要,理想情况下随后应尽早进行介入性内镜检查。现有内镜技术的最新进展使内镜医师能够根据临床情况选择治疗方法。注射硬化疗法仍然是出血患者的首选初始治疗方法。内镜下套扎术是一种替代方法,最好用于出血已自行停止的患者,或作为首次注射硬化疗法几天后的辅助治疗。组织粘合剂和凝血酶可用于治疗胃静脉曲张。[表格:见正文]如果没有内镜专业技术,药物治疗(使用生长抑素或奥曲肽)或气囊压迫是首选治疗方法。经颈静脉肝内门体分流术是一种新的有效技术,尚未广泛应用,其并发症发生率已记录在案,但尚未完全明确。对于尽管经过两次内镜干预仍继续出血的患者,作为“挽救”手术,它是手术的一个很好的替代方法。